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Study on effectiveness and user satisfaction of anti-inflammatory ointment of Curcuma albiflora Thw. in Bentota divisional secretariat, Southern Sri Lanka

Authors:

H. M. I. C. Herath ,

University of Colombo, LK
About H. M. I. C.
Faculty of Graduate Studies
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T. D. C. M. K. Wiyasiriwardene,

Industrial Technology Institute, Bauddaloka Mawatha, Colombo, LK
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G. A. S. Premakumara

Industrial Technology Institute, Bauddaloka Mawatha, Colombo, LK
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Abstract

Under the same Sinhalese vernacular name, three plants (Curcuma albiflora Thw., Curcuma zedoaria Rosc., and Zingiber zerumbet Smith.) are being reported. Amongst them, C. albiflora is an endangered and less explored plant. The current study was conducted to study anti-inflammatory activity of the ointment, which was produced using C. albiflora. Clinical trial was conducted using 175 participants in community based centers (n=2) in Grama Niladari divisions of Bentota Divisional Secretariat, Southern Province, Sri Lanka. Participants who were given treatment (98 patients) and the placebo (77 patients) were asked to complete the structured questionnaire. Treatment was applied for two weeks and the results were monitored by two Ayurvedic doctors who were involved in the study. Comparisons by chi square test showed that TM users differed from non-users in terms of previous side effects and current inflammatory condition (P<0.05). By binary logistic regression analysis, a treatment group satisfaction was about 31 times the chance of the placebo group. The models indicated that patients above 60 years of age, female, previous traditional medicine users, duration of current anti-inflammatory condition (≥ 1 year) were more likely to effectively response to the treatment. Ointment of C. albiflora Thw. showed moderate anti-inflammatory activity.
How to Cite: Herath, H.M.I.C., Wiyasiriwardene, T.D.C.M.K. and Premakumara, G.A.S., 2018. Study on effectiveness and user satisfaction of anti-inflammatory ointment of Curcuma albiflora Thw. in Bentota divisional secretariat, Southern Sri Lanka. Ruhuna Journal of Science, 9(2), pp.140–149. DOI: http://doi.org/10.4038/rjs.v9i2.42
Published on 31 Dec 2018.
Peer Reviewed

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